Bachelor-/ Master Thesis: »Development of a sampling platform for stem cell cultivation«

The Fraunhofer-Gesellschaft (www.fraunhofer.com) currently operates 76 institutes and research institutions throughout Germany and is the world’s leading applied research organization. Around 32,000 employees work with an annual research budget of 3.4 billion euros.

At the Fraunhofer IPT in Aachen, we work with more than 500 employees every day to make the production of the future more digital, more flexible and more sustainable. In the group »Automation in Life Sciences«, we develop fully automated production platforms for manufacturing complex medical and pharmaceutical products. One example of this is cell therapies based on stem cells, which have regenerative properties. These cell therapies can be produced in bioreactors, for example. During cultivation, samples should be taken daily for quality control. Conventional sampling systems usually do not function double-aseptically or only once and then must be reloaded manually. However, in the reactor cultivation of stem cells, daily analysis of samples is essential for maintaining high product quality. To enable scalable, industrial production the automation of sampling is necessary. Accordingly, we would like to develop a novel sampling system that allows double-aseptic samples to be taken multiple times over a longer period of time.

Within the scope of your thesis, you will design such a system based on an existing concept.

The job requires regular attendance at our institute in Aachen.

What you will do

• Independent familiarization with the topic
• Creation of a requirements and functional specifications document
• Research into existing approaches
• Design, implementation, and validation of a sampling platform

What you bring to the table

• You are studying mechanical engineering, industrial engineering, or a comparable field of study
• Initial experience in CAD, ideally SolidWorks
• An independent, structured way of working and problem-solving skills
• Very good language skills in German and English

What you can expect

• Insights into innovative research and industry projects
• Professional guidance and technical support in writing your thesis
• You are part of the team from the start and can contribute your own ideas

Interested? Apply online now. We look forward to getting to know you!

For any further information on this position please contact:
Lena Felser M.Sc.
Research assistant »Bio-adaptive Production«
Phone: +49 241 8904-783